Protein Homeostasis and Dynamics Group

We are a molecular systems biology lab focused on understanding protein dynamics and cellular processes through proteomics and bioinformatics approaches.

Research Focus

We take an interdisciplinary approach that combines proteomics technology with biological inquiries

Spatiotemporal proteomics
Spatiotemporal proteomics

Understanding the subcellular regulations of protein homeostasis

RNA protein correlations
RNA protein correlations

Machine learning and deep learning methods to predict proteins from mRNA

Protein turnover kinetics
Protein turnover kinetics

We develop methods to measure protein synthesis and degradation flux

Edward Lau

Principal Investigator

Edward Lau

Ed Lau is an Associate Professor in the Department of Medicine of the University of Colorado School of Medicine. He is also a faculty member of the Integrated Physiology, Pharmacology & Molecular Medicine, and Cell, Stem Cell & Development PhD programs on campus. Ed received his BA degree in molecular …

Research Interests: Protein turnover, kinetic models

Lab Updates

Recent news and announcements

Nov 02, 2025
Our lab's graduate student Jay Pavelka has successfully passed their Comps exam! Congrats Jay!

Sep 26, 2024
Our lab has received a 2-year NHGRI award to study the post-transcriptional regulation of protein levels in cancer and cardiac cells.

May 17, 2024
Aidan Borkan has successfully defended his work for his BSBT Master's program Bioinformatics specialization certificate. Congratulations!
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