Journal Articles by M. P. Y. Lam


B. Pandi, S. Brenman, A. Black, D. C. M. Ng, E. Lau, and M. P. Y. Lam
Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart
J Proteome Res, 2024
RIS, BibTex
J. Currie, V. Manda, S. K. Robinson, C. Lai, V. Agnihotri, V. Hidalgo, R. W. Ludwig, K. Zhang, et al.
Simultaneous proteome localization and turnover analysis reveals spatiotemporal features of protein homeostasis disruptions
Nat Commun, 15(1), 2207, 2024
URL, PDF, RIS, BibTex
N. Kastury, V. Hidalgo, B. Pandi, L. Li, M. P. Y. Lam, and E. Lau
Senescence in human AC16 cardiac cells is associated with thymidine kinase induction and histone loss
MicroPubl Biol, 2023, 2023
URL, PDF, RIS, BibTex
V. Hidalgo, N. Kastury, C. W. Durham, J. Currie, M. Amaya, M. P. Y. Lam, and E. Lau
Co-culture with normal and senescent AC16 cardiomyocytes modulates fibrotic response in primary human ventricular fibroblasts
MicroPubl Biol, 2023, 2023
URL, PDF, RIS, BibTex
H. Srivastava, M. J. Lippincott, J. Currie, R. Canfield, M. P. Y. Lam, and E. Lau
Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners
PLoS Comput Biol, 18(11), e1010702, 2022
URL, PDF, RIS, BibTex
D. M. Eaton, R. M. Berretta, J. E. Lynch, J. G. Travers, R. D. Pfeiffer, M. L. Hulke, H. Zhao, A. R. H. Hobby, et al.
Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF
Am J Physiol Heart Circ Physiol, 323(4), H797-H817, 2022
RIS, BibTex
Y. Han, S. A. Wennersten, J. M. Wright, R. W. Ludwig, E. Lau, and M. P. Y. Lam
Proteogenomics reveals sex-biased aging genes and coordinated splicing in cardiac aging
Am J Physiol Heart Circ Physiol, 323(3), H538-H558, 2022
RIS, BibTex
Y. Han, L. Z. Li, N. L. Kastury, C. T. Thomas, M. P. Y. Lam, and E. Lau
Transcriptome features of striated muscle aging and predictability of protein level changes
Mol. Omics, 2021
URL, DOI, PDF, RIS, BibTex
T. Chour, L. Tian, E. Lau, D. Thomas, I. Itzhaki, O. Malak, J. Z. Zhang, X. Qin, et al.
Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies
JCI Insight, 6(7), 2021
RIS, BibTex
Y. Han, S. D. Wood, J. M. Wright, V. Dostal, E. Lau, and M. P. Y. Lam
Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart
J Mol Cell Cardiol, 154, 92-96, 2021
URL, RIS, BibTex
V. Dostal, S. D. Wood, C. T. Thomas, Y. Han, E. Lau, and M. P. Y. Lam
Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart
Sci Rep, 10(1), 18440, 2020
RIS, BibTex
E. Lau, Y. Han, D. R. Williams, C. T. Thomas, R. Shrestha, J. C. Wu, and M. P. Y. Lam
Splice-junction-based mapping of alternative isoforms in the human proteome
Cell reports, 29(11), 3751—3765.e5, 2019
URL, DOI, RIS, BibTex
E. Lau, V. Venkatraman, C. T. Thomas, J. C. Wu, J. E. V. Eyk, and M. P. Y. Lam
Identifying high-priority proteins across the human diseasome using semantic similarity
Journal of proteome research, 17(12), 4267—4278, 2018
URL, DOI, RIS, BibTex
E. Lau, Q. Cao, M. P. Y. Lam, J. Wang, D. C. M. Ng, B. J. Bleakley, J. M. Lee, D. A. Liem, et al.
Integrated Omics Dissection of Proteome Dynamics During Cardiac Remodeling
Nature communications, 9(1), 120, 2018
URL, DOI, PDF, RIS, BibTex
M. P. Y. Lam, E. Lau, D. C. M. Ng, D. Wang, and P. Ping
Cardiovascular proteomics in the era of big data: experimental and computational advances
Clinical proteomics, 13, 23, 2016
URL, DOI, RIS, BibTex
M. P. Y. Lam, V. Venkatraman, Y. Xing, E. Lau, Q. Cao, D. C. M. Ng, A. I. Su, J. Ge, et al.
Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems
Journal of proteome research, 15(11), 4126—4134, 2016
URL, DOI, RIS, BibTex
E. Lau, Q. Cao, D. C. M. Ng, B. J. Bleakley, T. U. Dincer, B. M. Bot, D. Wang, D. A. Liem, et al.
A large dataset of protein dynamics in the mammalian heart proteome
Scientific data, 3, 160015, 2016
URL, DOI, RIS, BibTex
M. P. Y. Lam, V. Venkatraman, Q. Cao, D. Wang, T. U. Dincer, E. Lau, A. I. Su, Y. Xing, et al.
Prioritizing Proteomics Assay Development for Clinical Translation
Journal of the American College of Cardiology, 66(2), 202—204, 2015
URL, DOI, RIS, BibTex
E. Lau, D. Huang, Q. Cao, T. U. Dincer, C. M. Black, A. J. Lin, J. M. Lee, D. Wang, et al.
Spatial and temporal dynamics of the cardiac mitochondrial proteome
Expert review of proteomics, 12(2), 133—146, 2015
URL, DOI, RIS, BibTex
D. Wang, D. A. Liem, E. Lau, D. C. M. Ng, B. J. Bleakley, M. Cadeiras, M. C. Deng, M. P. Y. Lam, et al.
Characterization of human plasma proteome dynamics using deuterium oxide
Proteomics. Clinical applications, 8(78), 610—619, 2014
URL, DOI, RIS, BibTex
N. Zong, P. Ping, E. Lau, H. J. Choi, D. C. Ng, D. Meyer, C. Fang, H. Li, et al.
Lysine ubiquitination and acetylation of human cardiac 20S proteasomes
Proteomics. Clinical applications, 8(78), 590—594, 2014
URL, DOI, RIS, BibTex
M. P. Y. Lam, D. Wang, E. Lau, D. A. Liem, A. K. Kim, D. C. M. Ng, X. Liang, B. J. Bleakley, et al.
Protein kinetic signatures of the remodeling heart following isoproterenol stimulation
The Journal of clinical investigation, 124(4), 1734—1744, 2014
URL, DOI, RIS, BibTex
M. P. Y. Lam, E. Lau, D. A. Liem, and P. Ping
Cyclophilin D and acetylation: a new link in cardiac signaling
Circulation research, 113(12), 1268—1269, 2013
URL, DOI, RIS, BibTex
M. P. Y. Lam, E. Lau, S. B. Scruggs, D. Wang, T.-Y. Kim, D. A. Liem, J. Zhang, C. M. Ryan, et al.
Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation
Journal of proteomics, 81, 15—23, 2013
URL, DOI, RIS, BibTex
T.-Y. Kim, D. Wang, A. K. Kim, E. Lau, A. J. Lin, D. A. Liem, J. Zhang, N. C. Zong, et al.
Metabolic labeling reveals proteome dynamics of mouse mitochondria
Molecular & cellular proteomics : MCP, 11(12), 1586—1594, 2012
URL, DOI, RIS, BibTex
M. P. Y. Lam, S. B. Scruggs, T.-Y. Kim, C. Zong, E. Lau, D. Wang, C. M. Ryan, K. F. Faull, et al.
An MRM-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue
Journal of proteomics, 75(15), 4602—4609, 2012
URL, DOI, RIS, BibTex
J. Zhang, A. Lin, J. Powers, M. P. Lam, C. Lotz, D. Liem, E. Lau, D. Wang, et al.
Perspectives on: SGP symposium on mitochondrial physiology and medicine: mitochondrial proteome design: from molecular identity to pathophysiological regulation
The Journal of general physiology, 139(6), 395—406, 2012
URL, DOI, RIS, BibTex
E. Lau, D. Wang, J. Zhang, H. Yu, M. P. Y. Lam, X. Liang, N. Zong, T.-Y. Kim, et al.
Substrate- and isoform-specific proteome stability in normal and stressed cardiac mitochondria
Circulation research, 110(9), 1174—1178, 2012
URL, DOI, RIS, BibTex
M. P. Y. Lam, E. Lau, S. Siu, D. C. M. Ng, R. P. W. Kong, P. C. N. Chiu, W. S. B. Yeung, C. Lo, et al.
Online combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples
Electrophoresis, 32(21), 2930—2940, 2011
URL, DOI, RIS, BibTex
S. Siu, M. P. Y. Lam, E. Lau, R. P. W. Kong, S. M. Y. Lee, and I. K. Chu
Fully automatable two-dimensional reversed-phase capillary liquid chromatography with online tandem mass spectrometry for shotgun proteomics
Proteomics, 11(11), 2308—2319, 2011
URL, DOI, RIS, BibTex
E. Lau, M. P. Y. Lam, S. Siu, R. P. W. Kong, W. L. Chan, Z. Zhou, J. Huang, C. Lo, et al.
Combinatorial use of offline SCX and online RP-RP liquid chromatography for iTRAQ-based quantitative proteomics applications
Molecular bioSystems, 7(5), 1399—1408, 2011
URL, DOI, RIS, BibTex
M. P. Y. Lam, S. Siu, E. Lau, X. Mao, H. Sun, P. C. N. Chiu, W. S. B. Yeung, D. M. Cox, et al.
Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization
Analytical and bioanalytical chemistry, 398(2), 791—804, 2010
URL, DOI, RIS, BibTex
H. Liu, E. Lau, M. P. Y. Lam, H. Chu, S. Li, G. Huang, P. Guo, J. Wang, et al.
OsNOA1/RIF1 is a functional homolog of AtNOA1/RIF1: implication for a highly conserved plant cGTPase essential for chloroplast function
The New phytologist, 187(1), 83—105, 2010
URL, DOI, RIS, BibTex
S. Siu, M. P. Y. Lam, E. Lau, W. S. B. Yeung, D. M. Cox, and I. K. Chu
N-linked glycoprotein analysis using dual-extraction ultrahigh-performance liquid chromatography and electrospray tandem mass spectrometry
Methods in molecular biology (Clifton, N.J.), 600, 133—143, 2009
URL, DOI, RIS, BibTex

Preprint


V. Dostal, S. Wood, C. Thomas, Y. Han, E. Lau, and M. P. Lam
Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart
bioRxiv, 2020
URL, DOI, RIS, BibTex
E. Lau, V. Venkatraman, C. Thomas, J. V. Eyk, and M. P. Lam
Identifying high-priority proteins across the human diseasome using semantic similarity
bioRxiv, 2018
URL, DOI, RIS, BibTex